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1

High throughput screen identifies IFN-γ-dependent inhibitors of Toxoplasma gondii growth

Radke, Joshua B, Carey, Kimberly L, Shaw, Subrata, Metkar, Shailesh, Mulrooney, Carol, Gale, Jennifer P, Bittker, Joshua A., Hilgraf, Robert, Comer, Eamon, Schreiber, Stuart L, Virgin, Herbert W., Per

Journal:

ACS Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 1.39 MB

english, 2018

2

Nucleic acid evolution and minimization by nonhomologous random recombination

Bittker, Joshua A., Le, Brian V., Liu, David R.

Journal:

Nature Biotechnology

Year:

2002

Language:

english

File:

PDF, 3.00 MB

english, 2002

3

Functional Dissection of sRNA Translational Regulators by Nonhomologous Random Recombination and In Vivo Selection

Jane M. Liu, Joshua A. Bittker, Maria Lonshteyn, David R. Liu

Journal:

Chemistry & Biology

Year:

2005

Language:

english

File:

PDF, 582 KB

english, 2005

4

Recent advances in the in vitro evolution of nucleic acids

Joshua A Bittker, Kevin J Phillips, David R Liu

Journal:

Current Opinion in Chemical Biology

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

5

Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates

Willmen Youngsaye, Benjamin Vincent, Cathy L. Hartland, Barbara J. Morgan, Sara J. Buhrlage, Stephen Johnston, Joshua A. Bittker, Lawrence MacPherson, Sivaraman Dandapani, Michelle Palmer, Luke Whites

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.79 MB

english, 2011

6

Identification of small-molecule inhibitors of Trypansoma cruzi replication

Andrew R. Germain, Leigh C. Carmody, Chris Dockendorff, Cristina Galan-Rodriguez, Ana Rodriguez, Stephen Johnston, Joshua A. Bittker, Lawrence MacPherson, Sivaraman Dandapani, Michelle Palmer, Stuart

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

7

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Michel Weïwer, Joshua A. Bittker, Timothy A. Lewis, Kenichi Shimada, Wan Seok Yang, Lawrence MacPherson, Sivaraman Dandapani, Michelle Palmer, Brent R. Stockwell, Stuart L. Schreiber, Benito Munoz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.87 MB

english, 2012

8

Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles

Willmen Youngsaye, Chris Dockendorff, Benjamin Vincent, Cathy L. Hartland, Joshua A. Bittker, Sivaraman Dandapani, Michelle Palmer, Luke Whitesell, Susan Lindquist, Stuart L. Schreiber, Benito Munoz

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.24 MB

english, 2012

9

Evolving BioAssay Ontology (BAO): modularization, integration and applications

Abeyruwan, Saminda, Vempati, Uma D, Küçük-McGinty, Hande, Visser, Ubbo, Koleti, Amar, Mir, Ahsan, Sakurai, Kunie, Chung, Caty, Bittker, Joshua A, Clemons, Paul A, Brudz, Steve, Siripala, Anosha, Moral

Journal:

Journal of Biomedical Semantics

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

10

Utility-Aware Screening with Clique-Oriented Prioritization

Swamidass, S. Joshua, Calhoun, Bradley T., Bittker, Joshua A., Bodycombe, Nicole E., Clemons, Paul A.

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 1.62 MB

english, 2012

11

Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis

Park, Sae Woong, Casalena, Dominick E., Wilson, Daniel J., Dai, Ran, Nag, Partha P., Liu, Feng, Boyce, Jim P., Bittker, Joshua A., Schreiber, Stuart L., Finzel, Barry C., Schnappinger, Dirk, Aldrich,

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 2.64 MB

english, 2015

12

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Kato, Nobutaka, Comer, Eamon, Sakata-Kato, Tomoyo, Sharma, Arvind, Sharma, Manmohan, Maetani, Micah, Bastien, Jessica, Brancucci, Nicolas M., Bittker, Joshua A., Corey, Victoria, Clarke, David, Derbys

Journal:

Year:

2016

Language:

english

File:

PDF, 8.44 MB

english, 2016

13

Identification of Highly Specific Diversity-Oriented Synthesis-Derived Inhibitors of Clostridium difficile

Duvall, Jeremy R., Bedard, Leanne, Naylor-Olsen, Adel M., Manson, Abigail L., Bittker, Joshua A., Sun, Wenye, Fitzgerald, Mark E., He, Zhenmin, Lee, Maurice D., Marie, Jean-Charles, Muncipinto, Giovan

Journal:

ACS Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 1.70 MB

english, 2017

14

The Drug Repurposing Hub: a next-generation drug library and information resource

Corsello, Steven M, Bittker, Joshua A, Liu, Zihan, Gould, Joshua, McCarren, Patrick, Hirschman, Jodi E, Johnston, Stephen E, Vrcic, Anita, Wong, Bang, Khan, Mariya, Asiedu, Jacob, Narayan, Rajiv, Made

Journal:

Nature Medicine

Year:

2017

Language:

english

File:

PDF, 429 KB

english, 2017

15

Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease

Leshchiner, Elizaveta S., Rush, Jason S., Durney, Michael A., Cao, Zhifang, Dančík, Vlado, Chittick, Benjamin, Wu, Huixian, Petrone, Adam, Bittker, Joshua A., Phillips, Andrew, Perez, Jose R., Shamji,

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.38 MB

english, 2017

16

GDC-0879, a BRAF V600E Inhibitor, Protects Kidney Podocytes from Death

Sieber, Jonas, Wieder, Nicolas, Clark, Abbe, Reitberger, Manuel, Matan, Sofia, Schoenfelder, Jeannine, Zhang, Jianming, Mandinova, Anna, Bittker, Joshua Adam, Gutierrez, Juan, Aygün, Ozan, Udeshi, Nam

Journal:

Cell Chemical Biology

Year:

2017

Language:

english

File:

PDF, 2.98 MB

english, 2017

17

High Throughput Screens to Identify Autophagy Inducers that Function by Disrupting Beclin 1/Bcl-2 Binding

Chiang, Wei-Chung, Wei, Yongjie, Kuo, Yi-Chun, Wei, Shuguang, Zhou, Anwu, Zou, Zhongju, Yehl, Jenna, Ranaghan, Matthew J, Skepner, Adam, Bittker, Joshua A., Perez, José R., Posner, Bruce A., Levine, B

Journal:

ACS Chemical Biology

Year:

2018

Language:

english

File:

PDF, 1.75 MB

english, 2018

18

ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans

Youngsaye, Willmen, Hartland, Cathy L, Morgan, Barbara J, Ting, Amal, Nag, Partha P, Vincent, Benjamin, Mosher, Carrie A, Bittker, Joshua A, Dandapani, Sivaraman, Palmer, Michelle, Whitesell, Luke, Li

Journal:

Beilstein Journal of Organic Chemistry

Year:

2013

File:

PDF, 379 KB

2013

19

ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans

Youngsaye, Willmen, Hartland, Cathy L, Morgan, Barbara J, Ting, Amal, Nag, Partha P, Vincent, Benjamin, Mosher, Carrie A, Bittker, Joshua A, Dandapani, Sivaraman, Palmer, Michelle, Whitesell, Luke, Li

Journal:

Beilstein Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 379 KB

english, 2013